Comprehensive up-to-date analyses

 

The conventional diagnoses are often supplemented by specific immunohistochemical and molecular biological methods, e.g. next generation sequencing. In many cases, only the combination of these methods enables the pathologist to define disease entities and to correlate them with functional properties. This applies, in particular, to oncology with regards to histogenesis, prognosis, and drug resistance, as well as to pathology of infectious diseases with queries about pathogen detection/classification, e.g. tuberculosis, viruses, fungi etc. - for details see the following link ####. To fullfil these tasks, specially trained staff is available.

 

The conventional diagnoses are often supplemented by specific immunohistochemical, molecular biological and artificial intelligence based methods, e.g. next generation sequencing, automated quantification of biomarkers. Fully automated immunohistochemical stainers and gene sequencer of the latest generation, approved by the U. S. Food and Drug Administration (FDA), are available to fulfill the requirements for modern tissue-based diagnostics, which often directs the therapy, e.g. hormone receptor/HER2 status of breast cancer, EGFR mutations of lung cancer, BRAF mutations of malignant melanoma, PD-L1 detsction in several tumor entities, tumor.

 

The lab is participating in round robin tests for quality in assessment of histology, immunohistochemistry and molecular analysespathology, more details see in Quality Management.